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Introduction to PBMC for cell immunotherapy

PBMC is an abbreviation for peripheral blood mononuclear cells. Note that here is the mononuclear cell, not the Monocyte monocyte, which refers to any peripheral blood cell that has a rounded nucleus. That is to say, PBMC is an immune lymphocyte derived from the blood of healthy animals.

These cells include lymphocytes (T cells, B cells, NK cells) and monocytes, and granulocytes (including neutrophils, basophils, and eosinophils) have multi-lobed nuclei, sometimes it is divided into this category [1].

Therefore, PBMC is not a kind of cell, but a mixed immune cell. And immune cells are the most important soldiers in the body against viral diseases. Lymphocytes, monocytes, and Neutrophil Granulocytes in PBMC have very strong anti-tumor (cancer cells) and anti-viral effects!

However, T cells and NK (Natural Killer) cells are most important lymphoid in PBMC.